Dienstag, 21. Juli 2009

Interphase: Mitosis set to Music




INTERPHASE
Mitosis Set to Music
Copyright 1990 T.H. Culhane Melodic Mnemonics


PROPHASE
METAPHASE
ANAPHASE
TELOPHASE
PROPHASE
METAPHASE
ANAPHASE
TELOPHASE
CYTOKENISIS…!”

(We INTERrupt this mitotic program for a brief INTERmission…
INTERPHASE

INTERPHASE
Mitosis set to Music

You’re in INTERPHASE when you grow
You’re in INTERPHASE ‘til DNA starts to REPLICATE
You’re in INTERPHASE when you grow
When you grow
Making PROTEINS in THREE PHASES
G1, S, and G2 STAGES
Then MITOSIS recreates us
CELLS DIVIDE, rejuvenate us
There are 4 mitotic phases:
Prophase
Metaphase
Anaphase
Telophase
You’re in INTERPHASE when you grow
You’re in INTERPHASE ‘til DNA starts to REPLICATE
In PROPHASE…
Your CHROMATIN condenses
coiling up to form distinctive CHROMOSOMES

The CENTRIOLES then REPLICATE and move into position at the POLES

The MEMBRANE of the NUCLEUS  dissolves within its CYTOPLASMIC home
And SPINDLES start to form anchored on CENTROMERES within the central zone
In METAPHASE,
the middle of the CELL is where the SPINDLES guide each CHROMOSOME
…on spider-web like THREADS that make the CENTROMERES line up at the EQUATOR…
… and later…
In ANAPHASE -
the CENTROMERES divide,
Each CHROMATID transforms into a CHROMOSOME in its own right…
And SPINDLE FIBERS drag them to the POLES
In TELOPHASE –
a new NUCLEAR MEMBRANE forms
Around each set of CHROMOSOMES
Their COLORED BODIES* start to fade away
MITOSIS is complete but now the cell must REPLICATE
It must divide!
That’s when CYTOKINESIS…
Splits the cell in two pieces…
Dividing your CYTOPLASM
And all your ORGANELLES…
Making from one cell two!
You’re in INTERPHASE when you grow
You’re in INTERPHASE ‘til DNA starts to REPLICATE
You’re in INTERPHASE when you grow
When you grow
Making PROTEINS in THREE PHASES
G1, S, and G2 STAGES
Then MITOSIS recreates us
CELLS DIVIDE, rejuvenate us
Cells divide and divide and divide ‘til we’re old…
Then your TELOMERES shorten like an ever dwindling fuse…
And though your consciousness resists, your cell cannot refuse
Mitosis stops, your cells shut down…
And here’s the really awful news:
One by one they stop dividing…
Bit by bit you find you’re DYING…
It’s the end of your SOMATIC LINE…
I hope you REPRODUCED in time!
“The only way to escape death that we know of (so far) is through MEIOSIS,,
– whereby you go and create HAPLOID GERM CELLS
that must combine with other HAPLOID GERM CELLS
from some other SOMATIC LINE
then these GAMETES DNA must RECOMBINE
and begin the process of MITOSIS all over again!
Uh…
it’s called “SEX”…
You’re in INTERPHASE when you grow
You’re in INTERPHASE until MITOSIS makes your CELLS DIVIDE again…
It’s  INTERPHASE when you grow
When you grow
When you grow
When you grow

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